Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261504 | 0.78 | MAPT (0.56) | IRAK4MAPTKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL16654449 | 0.77 | MAPT (0.54) | IRAK4MAPTKDM4ENPC1RAB9A | |
| SCHEMBL8717093 | 0.76 | SMN1; SMN2 (0.51) | MAPTCTSDNPC1RAB9AHTT | |
| SCHEMBL27511872 | 0.74 | KDM4E (0.46) | IRAK4MAPTKDM4ECTSDNPC1 | |
| SCHEMBL9064369 | 0.73 | CA1 (0.52) | MAPTNPC1RAB9AHTTKMT2A | |
| SCHEMBL7827297 | 0.73 | HTT (0.49) | MAPTKDM4ECTSDNPC1RAB9A | |
| SCHEMBL7898666 | 0.72 | HPGD (0.48) | MAPTKDM4ENPC1RAB9AHTT | |
| Alcohol SCHEMBL6835135 | 0.72 | CTSD (0.62) | IRAK4MAPTKDM4ECTSDNPC1 | |
| SCHEMBL17911624 | 0.71 | MCHR1 (0.34) | LMNACHRM2 | |
| SCHEMBL1135994 | 0.71 | CTSD (0.49) | IRAK4MAPTCTSDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776963-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-07 | — | — | US | disclosed |