Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062573 | 0.81 | SMN1; SMN2 (0.77) | SMN1; SMN2PLAULMNAMAPTMEN1 | |
| SCHEMBL261504 | 0.80 | MAPT (0.56) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL17275012 | 0.80 | LMNA (0.57) | SMN1; SMN2LMNAMAPTMEN1NR1I2 | |
| SCHEMBL11552814 | 0.79 | KMT2A (0.67) | SMN1; SMN2LMNAMAPTMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL16654449 | 0.78 | MAPT (0.54) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL28821678 | 0.78 | LMNA (0.50) | SMN1; SMN2LMNAMAPTMEN1NR1I2 | |
| SCHEMBL27731656 | 0.78 | LMNA (0.66) | SMN1; SMN2LMNAMAPTMEN1NR1I2 | |
| SCHEMBL3079261 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2PLAULMNAMAPTMEN1 | |
| SCHEMBL8717088 | 0.76 | IRAK4 (0.44) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL27275371 | 0.76 | NPC1 (0.43) | SMN1; SMN2LMNAMAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776963-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-07 | — | — | US | disclosed |