Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284462 | 0.92 | CA1 (0.51) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL537424 | 0.89 | CA1 (0.61) | CA1CA2CA7CA9CASR | |
| SCHEMBL2235140 | 0.89 | CA1 (0.61) | CA1CA2CA7CA9CASR | |
| SCHEMBL1096481 | 0.89 | CA1 (0.61) | CA1CA2CA7CA9CASR | |
| SCHEMBL8752216 | 0.89 | L3MBTL1 (0.45) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL10417501 | 0.88 | KMT2A (0.49) | KMT2AMEN1L3MBTL1CASRNPC1 | |
| SCHEMBL19522241 | 0.85 | SLC6A1 (0.44) | KMT2AMEN1 | |
| SCHEMBL2771845 | 0.85 | CA1 (0.48) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL20742531 | 0.82 | CTSK (0.39) | CA1CA2KMT2AMEN1CA7 | |
| SCHEMBL20742533 | 0.82 | CTSK (0.39) | CA1CA2KMT2AMEN1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854228-A | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-12-29 | — | — | US | disclosed |
| US-5650510-A | VIRICIDES OR ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-07-22 | — | — | US | disclosed |