SCHEMBL871730

SCHEMBL871730

CC(=O)C(C(O)=S)N1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
PKM P14618 1/20 0.35
SLC1A2 P43004 1/20 0.34
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7164891 0.78 CYP2D6 (0.33) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL17541395 0.76 GSK3A (0.31)
SCHEMBL23716973 0.73 ALDH1A1 (0.46) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL8629351 0.72 ALDH1A1 (0.42) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL18020563 0.70 SLC1A2 (0.45) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL4147046 0.69 GLA (0.31)
SCHEMBL31723977 0.67 LMNA (0.37) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL57078 0.66 KMT2A (0.53) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL1564214 0.66 KMT2A (0.53) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL31259418 0.64 ALDH1A1 (0.46) ALDH1A1PKMSLC1A2KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011159735-A2 TETRANOR-PGDM/PGJM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME CAYMAN CHEMICAL COMPANY, INCORPORATED (US) 2011-12-22 WO claimed
US-20240366712-A1 GRIFFITHSIN FOR USE IN A METHOD OF PREVENTING OR TREATING INFECTIONS WITH RESPIRATORY VIRUSES Solmic Biotech GmbH (DE) 2024-11-07 US disclosed
US-20240110220-A1 DETECTING BETA-LACTAMASE ENZYME ACTIVITY COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-04-04 US disclosed
CN-117677401-A Gariferson for use in a method of preventing or treating a respiratory viral infection 索米克生物技术有限公司 2024-03-08 CN disclosed
CN-117015613-A Detection of beta-lactamase activity 原子能和代替能源委员会 2023-11-07 CN disclosed
EP-3893937-A2 HERBOXIDIENE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2021-10-20 EP disclosed
WO-2020123836-A2 HERBOXIDIENE SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2020-06-18 WO disclosed
EP-2150282-B1 COMPOSITIONS AND METHODS FOR SCAFFOLD FORMATION REGENTIS BIOMATERIALS LTD (IL) 2018-04-11 EP disclosed
US-20170182214-A1 COMPOSITIONS AND METHODS FOR SCAFFOLD FORMATION REGENTIS BIOMATERIALS LTD. (IL) 2017-06-29 US disclosed
US-9624259-B2 Compositions and methods for scaffold formation REGENTIS BIOMATERIALS LTD. (IL) 2017-04-18 US disclosed
US-20010044147-A1 Synthetic biodegradable amphipathic lipids, may include targeting agents CELL GENESYS, INC. 2001-11-22 US disclosed
US-6270983-B1 FOR USE IN IMMUNOASSAYS BIOTEZ BERLIN-BUCH GMBH (DE) 2001-08-07 US disclosed
EP-0833613-A1 DELIVERY VEHICLES COMPRISING STABLE LIPID/NUCLEIC ACID COMPLEXES SOMATIX THERAPY CORPORATION (US) 1998-04-08 EP disclosed
WO-1996037194-A1 DELIVERY VEHICLES COMPRISING STABLE LIPID/NUCLEIC ACID COMPLEXES SOMATIX THERAPY CORPORATION (US) 1996-11-28 WO disclosed
US-5567432-A MEMBRANE ENCAPSULATED BY SYNTHETIC NEUMAMINIC ACID RESIDUE;RETICULOENDOTHELIAL SYSTEM SDG, INC. 1996-10-22 US disclosed
US-5369006-A Determination of CK isoenzymes and CK isoforms E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-29 US disclosed
EP-0366770-B1 LIPOSOMES COUPLED TO HORMONES VESTAR INC (US) 1994-02-09 EP disclosed
WO-1993004374-A1 DETERMINATION OF CREATINE KINASE ISOENZYMES AND CREATINE KINASE ISOFORMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed
US-5080896-A Adjuvant Coupled to Antigen AKZO N. V. (NL) 1992-01-14 US disclosed
EP-0367166-A1 Modified interleukin-2 and production thereof Takeda Chemical Industries, Ltd. (JP) 1990-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010044147-A1 Synthetic biodegradable amphipathic lipids, may include targeting agents SGMS2, ABHD16A, PHOSPHO1 ALDH1A1 4819/4885PKM 2110/4885SLC1A2 2959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.