Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7604196 | 0.99 | SLC6A1 (0.52) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL6696529 | 0.88 | SLC6A1 (0.60) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL5498837 | 0.88 | SLC6A1 (0.60) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL3063792 | 0.88 | SLC6A1 (0.60) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL6956415 | 0.87 | ALDH1A1 (0.60) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL8196337 | 0.87 | ALDH1A1 (0.60) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL8717428 | 0.87 | TBXA2R (0.60) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL7609379 | 0.86 | TBXA2R (0.59) | ALDH1A1LMNA | |
| SCHEMBL6957114 | 0.86 | SLC6A1 (0.44) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL6963106 | 0.86 | SLC6A1 (0.44) | SLC6A1CYP1A2CYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869777-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997022338-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |