Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720199 | 0.76 | HTT (0.38) | ALDH1A1MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL8718069 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNASTING1 | |
| SCHEMBL8719860 | 0.72 | STING1 (0.41) | ALDH1A1MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL8718584 | 0.66 | NPC1 (0.41) | ALDH1A1MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL31564105 | 0.64 | BTK (0.40) | CA1CA2DRD2 | |
| SCHEMBL21597724 | 0.63 | CA1 (0.56) | ALDH1A1POLBCA1CA2ACHE | |
| SCHEMBL21597643 | 0.63 | CA1 (0.56) | ALDH1A1POLBCA1CA2ACHE | |
| SCHEMBL8718179 | 0.62 | MTNR1A (0.44) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL21597657 | 0.61 | MAPT (0.55) | ALDH1A1POLBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL21597712 | 0.61 | KDM4E (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |