Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718028 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDMTNR1AMTNR1BCA1 | |
| SCHEMBL8719860 | 0.75 | STING1 (0.41) | ALDH1A1MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL8718069 | 0.75 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL31564412 | 0.72 | PARP1 (0.39) | HTTALDH1A1HPGDL3MBTL1DRD2 | |
| SCHEMBL31563964 | 0.71 | ALDH1A1 (0.44) | HTTALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL31563897 | 0.68 | DRD2 (0.40) | HTTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL8718179 | 0.68 | MTNR1A (0.44) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL31563929 | 0.68 | CTSK (0.40) | HTTALDH1A1HPGDL3MBTL1CA1 | |
| SCHEMBL31564232 | 0.68 | DRD2 (0.40) | L3MBTL1DRD2 | |
| SCHEMBL8714966 | 0.68 | MTNR1A (0.33) | HTTALDH1A1HPGDL3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |