Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715494 | 0.80 | CHRNB2 (0.37) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL8715450 | 0.78 | CHRNB2 (0.40) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL9057427 | 0.77 | HTR2A (0.46) | SLC6A3KCNH2CACNA1CMTORRAB9A | |
| SCHEMBL16506377 | 0.76 | EPHX2 (0.37) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL4131850 | 0.76 | SRC (0.37) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL20818660 | 0.76 | CYP24A1 (0.36) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL6643895 | 0.75 | HTR2A (0.39) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL14936044 | 0.72 | GSR (0.46) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL2701320 | 0.72 | CHRNB2 (0.50) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL9220265 | 0.71 | TSHR (0.44) | LMNAMTORRAB9ACYP3A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | claimed |
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-5556821-A | Catalyst component for the polymerization of olefins | NIPPON OIL COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |