Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226244 | 0.80 | TSHR (0.43) | TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL10541121 | 0.79 | TSHR (0.46) | TSHRTAAR1HTR2ADPP4HRH1 | |
| SCHEMBL9227730 | 0.78 | CHRNA7 (0.35) | TSHRALDH1A1LMNA | |
| SCHEMBL9057427 | 0.78 | HTR2A (0.46) | TSHRTAAR1HTR2ADPP4HRH1 | |
| SCHEMBL9225482 | 0.78 | TSHR (0.37) | TSHRTAAR1HTR2A | |
| SCHEMBL9220176 | 0.77 | TSHR (0.35) | TSHR | |
| SCHEMBL11880794 | 0.76 | TSHR (0.42) | TSHRTAAR1HTR2AHRH1RIPK1 | |
| SCHEMBL3805595 | 0.74 | TSHR (0.41) | TSHRTAAR1HTR2AHRH1RIPK1 | |
| SCHEMBL7932298 | 0.74 | ALDH1A1 (0.48) | TSHRALDH1A1 | |
| SCHEMBL10885263 | 0.73 | TSHR (0.50) | TSHRTAAR1HTR2ADPP4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420987-A1 | Process for preparing fluoroalkyl derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | claimed |
| EP-0420987-B1 | Process for preparing fluoroalkyl derivatives | NIPPON OILS & FATS CO LTD (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5118879-A | Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0420987-A1 | Process for preparing fluoroalkyl derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | disclosed |