Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865833 | 0.78 | LMNA (0.52) | RAB9A | |
| SCHEMBL381296 | 0.78 | SCN4A (0.45) | DPP4F2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL18675977 | 0.78 | HTR2A (0.36) | HTR2ATAAR1HRH1DPP4TSHR | |
| SCHEMBL9220265 | 0.78 | TSHR (0.44) | HTR2ATAAR1HRH1DPP4TSHR | |
| SCHEMBL11066670 | 0.78 | CES2 (0.37) | HTR2ATAAR1HRH1DPP4TSHR | |
| SCHEMBL13851912 | 0.78 | TAAR1 (0.52) | TAAR1HRH1ALDH1A1CACNA1FCHRM2 | |
| SCHEMBL4601134 | 0.78 | TAAR1 (0.52) | TAAR1HRH1ALDH1A1CACNA1FCHRM2 | |
| SCHEMBL22713230 | 0.78 | SCN4A (0.45) | DPP4F2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL21216505 | 0.78 | TAAR1 (0.52) | TAAR1HRH1ALDH1A1CACNA1FCHRM2 | |
| SCHEMBL11137800 | 0.77 | HRH1 (0.52) | HTR2ATAAR1HRH1SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215476-B1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA LTD (CH) | 2017-11-09 | — | — | US | disclosed |
| US-9809596-B1 | Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis | LONZA LTD. (CH) | 2017-11-07 | — | — | US | disclosed |
| EP-3215476-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | Lonza Ltd (CH) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016071425-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA LTD (CH) | 2016-05-12 | — | — | WO | disclosed |
| WO-1996014283-A1 | PROCESS AND INTERMEDIATES FOR PREPARING TRIPHENYLTRIFLUOROPROPANES AND -PROPENES | EGIS Gyógyszergyár Rt. (HU) | 1996-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | AOC1, HDHD5, DDT | HTR2A 2353/4885TAAR1 108/4885HRH1 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.