Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715367 | 0.88 | FFAR1 (0.51) | PPARGFFAR1CA2PTPN1MAPT | |
| SCHEMBL9570555 | 0.88 | CA2 (0.48) | PPARGFFAR1CA2PTPN1MAPT | |
| SCHEMBL13846806 | 0.87 | CA2 (0.47) | PPARGFFAR1CA2PTPN1MAPT | |
| SCHEMBL4099376 | 0.85 | PPARG (0.46) | PPARGFFAR1CA2CNR2PTPN1 | |
| SCHEMBL13846718 | 0.84 | CNR2 (0.47) | PPARGFFAR1CA2CNR2PTPN1 | |
| SCHEMBL13846741 | 0.84 | PPARG (0.51) | PPARGFFAR1CA2PTPN1MAPT | |
| SCHEMBL9570547 | 0.84 | PPARG (0.57) | PPARGFFAR1CYP3A4MAPTPPARA | |
| SCHEMBL13846788 | 0.84 | CNR2 (0.46) | PPARGFFAR1CA2CNR2PTPN1 | |
| SCHEMBL13846795 | 0.83 | SLC2A1 (0.47) | PPARGFFAR1CA2CNR1CNR2 | |
| SCHEMBL7723276 | 0.83 | PPARG (0.42) | PPARGFFAR1CA2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042691-A1 | NEW THIAZOLEDINEDIONES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICAMENTS CONTAINING THE SAME | ROCHE DIAGNOSTICS GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |