Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716102 | 0.81 | SLC6A1 (0.65) | SLC6A1 | |
| SCHEMBL8712827 | 0.79 | LTA4H (0.46) | SLC6A1 | |
| SCHEMBL8712871 | 0.77 | LTA4H (0.57) | SLC6A1 | |
| SCHEMBL8695235 | 0.75 | LTA4H (0.57) | CYP2D6HTT | |
| SCHEMBL8718182 | 0.74 | SLC6A1 (0.59) | SLC6A1 | |
| SCHEMBL8718270 | 0.74 | SLC6A1 (0.43) | SLC6A1 | |
| SCHEMBL8715436 | 0.74 | SLC6A1 (0.47) | SLC6A1 | |
| SCHEMBL11171280 | 0.74 | CYP2D6 (0.50) | CYP2D6SLC6A1HTTMAPT | |
| SCHEMBL5502037 | 0.73 | SLC6A1 (0.55) | SLC6A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8718619 | 0.73 | LTA4H (0.52) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820442-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-01-28 | — | — | EP | claimed |
| WO-1996031474-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |