Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685369 | 0.93 | LTA4H (0.46) | LTA4HSLC6A1HRH1 | |
| SCHEMBL8712871 | 0.88 | LTA4H (0.57) | LTA4HSLC6A1SIGMAR1 | |
| SCHEMBL8690299 | 0.88 | LTA4H (0.45) | LTA4HSLC6A1HRH1 | |
| SCHEMBL8716401 | 0.86 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8690225 | 0.85 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8718619 | 0.81 | LTA4H (0.52) | LTA4HSLC6A1 | |
| SCHEMBL8718270 | 0.81 | SLC6A1 (0.43) | SLC6A1SIGMAR1 | |
| SCHEMBL8715531 | 0.80 | HTR2C (0.44) | — | |
| SCHEMBL8716102 | 0.80 | SLC6A1 (0.65) | SLC6A1 | |
| SCHEMBL8718374 | 0.79 | CYP2D6 (0.45) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | claimed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |