Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718613 | 0.76 | MAPT (0.39) | NOTUMNPC1RAB9ATSHRKMT2A | |
| SCHEMBL7852977 | 0.70 | NPC1 (0.50) | NOTUMNPC1RAB9ATP53TSHR | |
| SCHEMBL817554 | 0.70 | ALOX5 (0.65) | NOTUMNPC1RAB9AMAOBTP53 | |
| SCHEMBL31222672 | 0.70 | ALOX5 (0.65) | NOTUMNPC1RAB9AMAOBTP53 | |
| SCHEMBL27648776 | 0.69 | NOTUM (0.42) | NOTUMNPC1RAB9ATP53TSHR | |
| SCHEMBL11579010 | 0.68 | ESR2 (0.41) | NOTUMNPC1RAB9AMAOBKMT2A | |
| SCHEMBL11771739 | 0.68 | TDO2 (0.41) | NOTUMTAAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31070804 | 0.67 | ALOX5 (0.62) | NOTUMNPC1RAB9AMAOBTP53 | |
| SCHEMBL29629014 | 0.67 | ALOX5 (0.62) | NOTUMNPC1RAB9AMAOBTP53 | |
| Hydrochloric Acid SCHEMBL28332867 | 0.67 | ALOX5 (0.62) | NOTUMNPC1RAB9AMAOBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985765-A | ANTIINFLAMMATORY OR ANTIPYRETIC ACTIVITY | MILES LABORATORIES, INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3948930-A | ANTIINFLAMMATORY, ANTIPYRETIC | MILES LABORATORIES, INC. (US) | 1976-04-06 | — | — | US | disclosed |
| US-3948929-A | ANTIINFLAMMATORY, ANTIPYRETIC | MILES LABORATORIES, INC. (US) | 1976-04-06 | — | — | US | disclosed |
| US-3948932-A | ANTIINFLAMMATORY, ANTIPYRETIC | MILES LABORATORIES, INC. (US) | 1976-04-06 | — | — | US | disclosed |