Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872153 | 0.85 | HTT (0.41) | USP2MAPTTSHRSMN1; SMN2NPSR1 | |
| SCHEMBL8718771 | 0.85 | MMP13 (0.36) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8721252 | 0.82 | PTGS1 (0.40) | SMN1; SMN2 | |
| SCHEMBL8723274 | 0.78 | USP2 (0.46) | USP2MAPTTSHRCYP1A2CYP2C19 | |
| SCHEMBL8718743 | 0.78 | USP2 (0.46) | USP2MAPTTSHRCYP1A2CYP2C19 | |
| SCHEMBL8718610 | 0.77 | POLB (0.39) | MAPTTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL8721136 | 0.73 | L3MBTL1 (0.51) | MAPTRECQLL3MBTL1 | |
| SCHEMBL22710206 | 0.69 | MAPT (0.55) | USP2MAPTTSHRCYP1A2CYP2C19 | |
| SCHEMBL13610242 | 0.69 | MAPT (0.55) | USP2MAPTTSHRCYP1A2CYP2C19 | |
| SCHEMBL3235736 | 0.68 | ATM (0.47) | MAPTCYP2C9NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567982-B1 | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5466820-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0567982-A1 | Azole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |