Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721252 | 0.87 | PTGS1 (0.40) | SMN1; SMN2NPBWR1MCHR1PRMT1PTGS1 | |
| SCHEMBL8718629 | 0.85 | USP2 (0.46) | SMN1; SMN2USP2MAPTTSHRL3MBTL1 | |
| SCHEMBL8718771 | 0.84 | MMP13 (0.36) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL8718610 | 0.81 | POLB (0.39) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL8718627 | 0.80 | HTT (0.41) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL8721136 | 0.76 | L3MBTL1 (0.51) | ALDH1A1MAPTNPBWR1MCHR1POLB | |
| SCHEMBL8105481 | 0.75 | HTT (0.39) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL6174527 | 0.75 | HTT (0.46) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL7686964 | 0.75 | HTT (0.39) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL8872291 | 0.74 | SMN1; SMN2 (0.42) | HTTKMT2ASMN1; SMN2ALDH1A1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677464-A | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5466820-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0659751-A1 | Optically active azole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |