Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 10/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411552 | 0.98 | KDM4E (0.47) | KDM4EOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL2078485 | 0.95 | HTR3A (0.46) | KDM4EOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL31429395 | 0.92 | CYP3A4 (0.44) | KDM4EOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL8718851 | 0.87 | HTR3A (0.44) | KDM4EOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL5316749 | 0.86 | SSTR4 (0.49) | — | |
| SCHEMBL8876610 | 0.85 | ELANE (0.51) | KDM4EOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL8713323 | 0.85 | HTR3A (0.45) | KDM4EMEN1KMT2ACNR1CNR2 | |
| SCHEMBL719399 | 0.83 | ELANE (0.53) | KDM4EMEN1KMT2ACNR1HTR3E | |
| SCHEMBL8717365 | 0.82 | HTR3A (0.48) | KDM4EOPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL21725181 | 0.82 | ELANE (0.54) | KDM4ECNR1HTR3ESLC22A2HTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |