Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714252 | 0.83 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19TSHRSLC6A2 | |
| SCHEMBL8719972 | 0.81 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19TSHRSLC6A2 | |
| SCHEMBL3663149 | 0.77 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL4544073 | 0.74 | KIF11 (0.52) | CYP1A2CYP2C9CYP2C19TSHRTAAR1 | |
| SCHEMBL9408952 | 0.74 | TSHR (0.44) | CYP1A2CYP2C9CYP2C19TSHRTAAR1 | |
| SCHEMBL19027533 | 0.73 | CYP2C9 (0.41) | CYP1A2CYP2C9CYP2C19TSHRSLC6A2 | |
| SCHEMBL1505807 | 0.72 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL8569751 | 0.71 | MAPK1 (0.41) | CYP1A2CYP2C9CYP2C19TSHRTAAR1 | |
| SCHEMBL324079 | 0.70 | SLC6A2 (0.50) | CYP1A2CYP2C9CYP2C19TSHRSLC6A2 | |
| SCHEMBL4413010 | 0.69 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |