SCHEMBL8719972

SCHEMBL8719972

FC(F)(F)COC(Cc1ccccc1)(OCC(F)(F)F)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
PTPN1 P18031 1/20 0.41
CETP P11597 3/20 0.37
TACR1 P25103 1/20 0.36
IDO1 P14902 2/20 0.36
SLC6A2 P23975 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
KIF11 P52732 1/20 0.35
KCNA5 P22460 1/20 0.34
MAOB P27338 1/20 0.34
CHRM1 P11229 3/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8714252 0.83 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL8718960 0.81 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19TSHRPTPN1
SCHEMBL3663149 0.77 CYP1A2 (0.45) CYP1A2CYP2C9CYP2C19ALDH1A1PTPN1
SCHEMBL5670917 0.75 ALDH1A1 (0.39) ALDH1A1TSHRPTPN1TACR1KIF11
SCHEMBL5872334 0.74 KIF11 (0.52) ALDH1A1TSHRPTPN1TACR1IDO1
SCHEMBL9078324 0.74 TSHR (0.50) ALDH1A1TSHRPTPN1TACR1IDO1
SCHEMBL19027533 0.73 CYP2C9 (0.41) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL1505807 0.72 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL5670904 0.71 PTPN1 (0.36) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL8566517 0.71 ALDH1A1 (0.46) CYP2C19ALDH1A1TSHRPTPN1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed