SCHEMBL8719017

SCHEMBL8719017

COC(=O)C(Cl)=C(C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9073402 1.00
SCHEMBL11145544 0.80 ALDH1A1 (0.45)
SCHEMBL9720623 0.80 ALDH1A1 (0.45)
SCHEMBL9720619 0.80 ALDH1A1 (0.45)
SCHEMBL9720739 0.79 ALDH1A1 (0.36)
SCHEMBL9720747 0.79 ALDH1A1 (0.36)
SCHEMBL8571994 0.78
SCHEMBL8970856 0.76 ALDH1A1 (0.43)
SCHEMBL9321081 0.76 ALDH1A1 (0.43)
SCHEMBL11147128 0.76 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4199600-A INHIBITING GROWTH OF BACTERIA AND FUNGI, COSMETICS, OIL AND WATER EMULSIONS GIVAUDAN CORPORATION (US) 1980-04-22 US claimed
EP-0708758-B1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED HOECHST SCHERING AGREVO GMBH (DE) 1998-02-04 EP disclosed
US-5523404-A Process for preparing 5-chloro-4-hydroxypyrimidines HOECHST SCHERING AGREVO GMBH (DE) 1996-06-04 US disclosed
EP-0708758-A1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED Hoechst Schering AgrEvo GmbH (DE) 1996-05-01 EP disclosed
WO-1995001963-A1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED HOECHST SCHERING AGREVO GMBH (DE) 1995-01-19 WO disclosed
US-4199600-A INHIBITING GROWTH OF BACTERIA AND FUNGI, COSMETICS, OIL AND WATER EMULSIONS GIVAUDAN CORPORATION (US) 1980-04-22 US disclosed