Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21752110 | 0.76 | TP53 (0.63) | TP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7165139 | 0.76 | TP53 (0.63) | TP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8299971 | 0.75 | GRIN2B (0.62) | OPRM1OPRL1TP53 | |
| SCHEMBL30330305 | 0.73 | CYP2D6 (0.62) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6264793 | 0.73 | CTSS (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27502384 | 0.72 | NTSR1 (0.48) | CNR1OPRM1OPRL1TP53SLC6A2 | |
| SCHEMBL2769037 | 0.72 | SLC6A4 (0.43) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8251418 | 0.72 | SLC6A4 (0.43) | OPRM1OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8294013 | 0.70 | GRIN2B (0.59) | OPRM1OPRL1TP53 | |
| SCHEMBL27502385 | 0.70 | GMNN (0.42) | CNR1OPRM1OPRL1TP53SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848707-A1 | 4-(CYCLOALKYL)PIPERIDINES AND 4-(CYCLOALKYLALKYL)-PIPERIDINES DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997009309-A1 | 4-(CYCLOALKYL)PIPERIDINE AND 4-(CYCLOALKYLALKYL)PIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATIONS THEREOF | SYNTHELABO (FR) | 1997-03-13 | — | — | WO | disclosed |