SCHEMBL8719378

SCHEMBL8719378

CCNCc1ccccc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 2/20 0.42
CYP2D6 P10635 1/20 0.42
MYC P01106 1/20 0.42
CA12 O43570 8/20 0.42
CA2 P00918 7/20 0.42
CA9 Q16790 7/20 0.42
GAA P10253 1/20 0.41
KDM4E B2RXH2 1/20 0.38
ADRA1D P25100 2/20 0.38
CA1 P00915 1/20 0.37
MPO P05164 1/20 0.37
CTSB P07858 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
SLC2A1 P11166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11807158 0.82 CA12 (0.58) HSD17B10TSHRCYP2D6CA12CA2
SCHEMBL9768531 0.81 MYC (0.44) LMNAMYCCA2KDM4ECA1
SCHEMBL29394818 0.81 CTSB (0.52) HIF1AHSD17B10LMNAHPGDTSHR
SCHEMBL34582 0.81 CTSB (0.52) HIF1AHSD17B10LMNAHPGDTSHR
Phenolsulphonic Acid SCHEMBL3330404 0.80 HIF1A (0.65) HIF1AHSD17B10LMNAHPGDTSHR
SCHEMBL31319091 0.79 MYC (0.46) HIF1AHSD17B10LMNAHPGDTSHR
SCHEMBL150860 0.79 MYC (0.46) HIF1AHSD17B10LMNAHPGDTSHR
Ammonia Solution, Strong SCHEMBL23749173 0.79 CTSB (0.50) HIF1AHSD17B10LMNAHPGDTSHR
SCHEMBL2472813 0.79 CTSB (0.50) HIF1AHSD17B10LMNAHPGDTSHR
SCHEMBL28786667 0.79 CTSB (0.50) HIF1AHSD17B10LMNAHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710258-A Azo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-20 US disclosed