Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 9/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007490 | 0.86 | S1PR1 (0.46) | TRPV3MAPK1PDE4BPPARDTRPV1 | |
| SCHEMBL7009045 | 0.83 | ABCG2 (0.47) | MAPK1PDE4BCYP3A4CYP2D6SCN9A | |
| SCHEMBL7009043 | 0.73 | S1PR1 (0.53) | TRPV1SCN9AFPR2 | |
| SCHEMBL5214349 | 0.72 | PTGS2 (0.38) | PDE4BPPARDCYP3A4CYP2D6PSEN1 | |
| SCHEMBL7006071 | 0.71 | S1PR1 (0.48) | TRPV1SCN9AFPR2 | |
| SCHEMBL7009823 | 0.71 | S1PR1 (0.48) | MAPK1TRPV1SCN9AFPR2MAPT | |
| SCHEMBL13273290 | 0.70 | MAPT (0.45) | TRPV3PPARDMAPT | |
| SCHEMBL336755 | 0.69 | FFAR4 (0.52) | MAPK1TRPV1MAPT | |
| SCHEMBL29387718 | 0.69 | FFAR4 (0.52) | MAPK1TRPV1MAPT | |
| SCHEMBL8722892 | 0.68 | MAPK1 (0.43) | TRPV3MAPK1TRPV1SCN9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823431-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1998-02-11 | — | — | EP | claimed |
| EP-0823431-A1 | Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines | American Cyanamid Company (US) | 1998-02-11 | — | — | EP | disclosed |