SCHEMBL8719769

SCHEMBL8719769

CCOC(=O)c1cc2cc(C(=N)N)ccc2o1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPSAB1 Q15661 5/20 0.55
TPSD1 Q9BZJ3 5/20 0.55
TPSG1 Q9NRR2 5/20 0.55
F2 P00734 7/20 0.54
F10 P00742 1/20 0.54
ITGB3 P05106 3/20 0.50
ITGA2B P08514 3/20 0.50
F12 P00748 1/20 0.50
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
CASP3 P42574 1/20 0.49
RAB9A P51151 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
PRMT1 Q99873 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8718278 0.99 TPSAB1 (0.54) TPSAB1TPSD1TPSG1F2F10
SCHEMBL8905180 0.90 MEN1 (0.50) MEN1NPC1MAPTTSHRMAPK1
Hydrochloric Acid SCHEMBL8712944 0.88 ITGB3 (0.50) TPSAB1TPSD1TPSG1F2F10
SCHEMBL15155753 0.86 HRH3 (0.52) MEN1NPC1MAPTTSHRMAPK1
SCHEMBL28182751 0.86 MEN1 (0.51) MEN1NPC1MAPTTSHRMAPK1
SCHEMBL8719127 0.84 MEN1 (0.47) MEN1NPC1MAPTTSHRMAPK1
SCHEMBL3853096 0.82 MEN1 (0.47) MEN1NPC1MAPTTSHRMAPK1
SCHEMBL3853091 0.82 MEN1 (0.47) MEN1NPC1MAPTTSHRMAPK1
SCHEMBL1066982 0.81 TAS1R3 (0.56) MEN1MAPTKMT2AHSD17B10
SCHEMBL25777700 0.81 CA12 (0.59) MEN1MAPTKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753670-A ANTICOAGULANTS THE GREEN CROSS CORPORATION (JP) 1998-05-19 US disclosed
US-5635527-A ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES THE GREEN CROSS CORPORATION (JP) 1997-06-03 US disclosed
EP-0712844-A1 NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF THE GREEN CROSS CORPORATION (JP) 1996-05-22 EP disclosed