SCHEMBL8720

SCHEMBL8720

[SiH3]C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
TSHR P16473 2/20 0.50
F2 P00734 1/20 0.50
HTR2A P28223 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
CYP2D6 P10635 2/20 0.43
SRC P12931 1/20 0.43
LMNA P02545 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
HRH1 P35367 1/20 0.41
MTOR P42345 1/20 0.41
RAB9A P51151 1/20 0.41
GRM7 Q14831 1/20 0.41
MAPK1 P28482 1/20 0.41
SLC6A2 P23975 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2796772 0.96 DPP4 (0.47) DPP4TSHRF2HTR2ATAAR1
SCHEMBL2796782 0.96 DPP4 (0.47) DPP4TSHRF2HTR2ATAAR1
SCHEMBL2498568 0.79 LTA4H (0.57) TSHR
SCHEMBL2313234 0.76
SCHEMBL2239669 0.76
SCHEMBL992530 0.76
SCHEMBL6283476 0.74 TSHR (0.65) DPP4TSHRF2HTR2ATAAR1
SCHEMBL1534359 0.74 DPP4 (0.41) DPP4TSHRF2HTR2ATAAR1
SCHEMBL448348 0.72 DPP4 (0.53) DPP4TSHRF2HTR2ATAAR1
SCHEMBL144 0.72 SLC6A2 (0.67) DPP4TSHRF2HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13348 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US claimed
CN-119327447-A Stable Au and Pt catalyst based on crown ether and preparation and application thereof 中国科学院大连化学物理研究所 2025-01-21 CN claimed
WO-2024230099-A1 NEGATIVE ELECTRODE SHEET, PREPARATION METHOD THEREFOR, BATTERY CELL, BATTERY AND ELECTRICAL APPARATUS 宁德时代新能源科技股份有限公司 2024-11-14 WO claimed
CN-118638144-A Synthesis method of heteroaryl silane 南阳师范学院 2024-09-13 CN claimed
CN-114989031-B Preparation method for synthesizing unsaturated amide by carbon dioxide and alkyne 湖南工程学院 2024-08-20 CN claimed
EP-3930868-B1 COATED FLOW PATH COMPONENTS FOR CHROMATOGRAPHIC EFFECTS WATERS TECHNOLOGIES CORP (US) 2024-07-17 EP claimed
CN-118324823-A Heterofluorene rare earth compound, preparation method thereof and application thereof in olefin polymerization 中国科学院长春应用化学研究所 2024-07-12 CN claimed
WO-2024140294-A1 ORGANIC COMPOUND AND APPLICATION THEREOF IN OLED DEVICE 北京云基科技股份有限公司 2024-07-04 WO claimed
CN-118204010-A System and method for preparing silanol and hydrogen with high added value from silane 安徽大学 2024-06-18 CN claimed
EP-4373831-A1 PROCESSES FOR THE PREPARATION OF ESTETROL AND INTERMEDIATES THEREOF Newchem S.p.A. (IT) 2024-05-29 EP claimed
US-5328930-A Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin EMORY UNIVERSITY (US) 1994-07-12 US claimed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP claimed
US-5294737-A Hydrolysis, cyclization, condensation THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) 1994-03-15 US claimed
EP-0571087-A1 Cleavable phosphoramidites ROHM AND HAAS COMPANY (US) 1993-11-24 EP claimed
US-5075435-A Chemical intermediates for 1-methylcarbapenicillin SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1991-12-24 US claimed
US-5045428-A Encapsulated toner compositions and processes thereof XEROX CORPORATION (US) 1991-09-03 US claimed
US-4912242-A Process for preparing silicon esters DOW CORNING CORPORATION (US) 1990-03-27 US claimed
US-4394291-A COORDINATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1983-07-19 US claimed
US-3980803-A Linear phenylmethylsilicone oil as dielectric for stationary electric device TOKYO SHIBAURA ELECTRIC CO., LTD. (JA) 1976-09-14 US claimed
US-3943157-A Synthesis of codling moth attractant ZOECON CORPORATION (US) 1976-03-09 US claimed