Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717236 | 0.88 | GAA (0.36) | GAAMAPTIDO1L3MBTL1PDPK1 | |
| SCHEMBL9273636 | 0.83 | ALDH1A1 (0.35) | GAAMAPTL3MBTL1PDPK1AXL | |
| SCHEMBL8720058 | 0.73 | PIM1 (0.41) | GAAMAPTIDO1L3MBTL1PDPK1 | |
| SCHEMBL22801811 | 0.60 | FYN (0.43) | IDO1PDPK1DYRK1AFYN | |
| SCHEMBL8716395 | 0.60 | TOP2A (0.35) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL407793 | 0.57 | MAPT (1.00) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL12396548 | 0.56 | GAA (0.81) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8142848 | 0.55 | AURKA (0.45) | GAAIDO1DYRK1AFYN | |
| SCHEMBL17952723 | 0.55 | SMN1; SMN2 (0.45) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL4484831 | 0.54 | PIK3CA (0.43) | GAAL3MBTL1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837861-A1 | NEW PYRIDO-THIOPYRANOINDAZOLES WITH ANTITUMOR ACTIVITY | THE UNIVERSITY OF VERMONT (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997002267-A1 | NEW PYRIDO-THIOPYRANOINDAZOLES WITH ANTITUMOR ACTIVITY | UNIVERSITY OF VERMONT (US) | 1997-01-23 | — | — | WO | disclosed |