Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195816 | 0.84 | FFAR4 (0.59) | FFAR4TRPV1METAP2CA2GABRA3 | |
| SCHEMBL1952267 | 0.76 | CA2 (0.37) | FFAR4MTNR1ACA2PTPN1PTPN11 | |
| SCHEMBL3633717 | 0.72 | FLT1 (0.34) | FFAR4METAP2MTNR1ACA2PTPN1 | |
| SCHEMBL7739121 | 0.68 | CA2 (0.37) | FFAR4MTNR1ACA2PTPN1PTPN11 | |
| SCHEMBL7739123 | 0.68 | CA2 (0.50) | FFAR4CA2PTPN1PTPN11ALOX5 | |
| SCHEMBL23679879 | 0.68 | CA2 (0.37) | FFAR4MTNR1ACA2PTPN1PTPN11 | |
| SCHEMBL11800303 | 0.68 | CNR1 (0.43) | FFAR4METAP2MTNR1ACA2LMNA | |
| SCHEMBL7299326 | 0.68 | PTPN1 (0.36) | FFAR4MTNR1ACA2PTPN1PTPN11 | |
| SCHEMBL6618290 | 0.68 | CA2 (0.59) | FFAR4CA2LMNAPLK1CNR1 | |
| SCHEMBL1023215 | 0.68 | DHFR (0.45) | PTPN1PTPN11HPGDALOX5CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858336-A1 | METHOD AND PHARMACEUTICAL COMPOSITION FOR REGULATING LIPID CONCENTRATION | WARNER-LAMBERT COMPANY (US) | 1998-08-19 | — | — | EP | claimed |
| WO-1997016184-A1 | METHOD AND PHARMACEUTICAL COMPOSITION FOR REGULATING LIPID CONCENTRATION | WARNER-LAMBERT COMPANY (US) | 1997-05-09 | — | — | WO | claimed |