Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713335 | 0.88 | TAAR1 (0.44) | TAAR1IDO1AGXTKIF11 | |
| SCHEMBL8714023 | 0.83 | TRPA1 (0.46) | TAAR1SIGMAR1KIF11CYP1A2 | |
| SCHEMBL8713929 | 0.83 | KIF11 (0.41) | TAAR1IDO1KIF11GRM2GRM3 | |
| SCHEMBL8713860 | 0.82 | HTT (0.47) | SIGMAR1KIF11CYP1A2 | |
| SCHEMBL8716258 | 0.78 | SLC6A4 (0.44) | TAAR1IDO1AGXTKIF11CYP1A2 | |
| SCHEMBL8718475 | 0.77 | MAOB (0.48) | MAOBCYP1A2 | |
| SCHEMBL8716720 | 0.77 | CASR (0.49) | KIF11 | |
| SCHEMBL20228977 | 0.76 | MAOB (0.51) | TAAR1IDO1AGXTMAOBSIGMAR1 | |
| SCHEMBL8714231 | 0.75 | ESR1 (0.53) | TAAR1KIF11 | |
| SCHEMBL8713320 | 0.75 | ESR1 (0.38) | TAAR1KIF11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |