Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM3 | Q14832 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560134 | 0.94 | KDM1A (0.49) | GRM3ALDH1A1KDM1A | |
| SCHEMBL8410939 | 0.90 | GRM3 (0.50) | GRM3KMT2AALDH1A1KDM1APOLB | |
| SCHEMBL8407569 | 0.87 | CCNK (0.51) | GRM3ALDH1A1KDM1A | |
| SCHEMBL8407175 | 0.85 | GAA (0.47) | ALDH1A1KDM1APOLB | |
| Hydrochloric Acid SCHEMBL8407353 | 0.83 | KMT2A (0.47) | GRM3KMT2AALDH1A1KDM1APOLB | |
| SCHEMBL8409542 | 0.81 | MAOB (0.52) | KMT2AALDH1A1POLB | |
| SCHEMBL8715690 | 0.79 | LTA4H (0.48) | KDM1A | |
| SCHEMBL8407511 | 0.79 | MLNR (0.46) | ALDH1A1KDM1A | |
| SCHEMBL8407177 | 0.78 | HTT (0.40) | KDM1A | |
| Hydrochloric Acid SCHEMBL8407950 | 0.76 | ITGB3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |