Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720191 | 0.94 | GRM3 (0.54) | KDM1AALDH1A1GRM3 | |
| SCHEMBL8407569 | 0.93 | CCNK (0.51) | KDM1AALDH1A1CCNKCDK12NOS1 | |
| SCHEMBL8407511 | 0.85 | MLNR (0.46) | KDM1AALDH1A1 | |
| SCHEMBL8410939 | 0.83 | GRM3 (0.50) | KDM1AALDH1A1GRM3 | |
| SCHEMBL8719948 | 0.82 | KDM1A (0.49) | KDM1AALDH1A1CCNKCDK12NOS1 | |
| Hydrochloric Acid SCHEMBL8407950 | 0.82 | ITGB3 (0.46) | — | |
| SCHEMBL8949062 | 0.82 | CCNK (0.47) | EGLN1CCNKCDK12NOS1NOS2 | |
| SCHEMBL8718956 | 0.80 | MLNR (0.48) | KDM1AALDH1A1 | |
| SCHEMBL8409445 | 0.80 | CHRM4 (0.52) | KDM1AALDH1A1CCNKCDK12 | |
| SCHEMBL8407175 | 0.79 | GAA (0.47) | KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |