Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802680 | 0.87 | NSD2 (0.73) | LTA4HTSHRNSD2HSP90AA1HKDC1 | |
| SCHEMBL6256773 | 0.79 | LTA4H (0.50) | LTA4HTSHRNSD2HSP90AA1HKDC1 | |
| SCHEMBL6432470 | 0.78 | LTA4H (0.55) | LTA4HTSHRNSD2HSP90AA1HKDC1 | |
| Anthraquinone SCHEMBL28596353 | 0.78 | MEN1 (0.63) | LTA4HTSHRNSD2HSP90AA1HKDC1 | |
| Diphenylether SCHEMBL4950525 | 0.77 | LTA4H (1.00) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL2461810 | 0.77 | LTA4H (1.00) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL12286 | 0.77 | LTA4H (1.00) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL9061108 | 0.77 | LTA4H (1.00) | LTA4HTSHRCA1CA2CA9 | |
| SCHEMBL9654269 | 0.76 | CES2 (0.56) | NSD2HSP90AA1HKDC1TLR9CES2 | |
| (Phenylsulfonyl)Benzene SCHEMBL2126656 | 0.76 | HTT (0.70) | LTA4HTSHRHTTSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662004-B1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1998-03-18 | — | — | EP | disclosed |
| US-5700448-A | Use of persistent free-radicals in magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1997-12-23 | — | — | US | disclosed |
| US-5435991-A | Use of persistent heterocyclic free-radicals in magnetic resonance imaging | NYCOMED INNOVATION AB (SE) | 1995-07-25 | — | — | US | disclosed |
| EP-0662004-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | Nycomed Innovation AB (SE) | 1995-07-12 | — | — | EP | disclosed |
| EP-0355735-B1 | Water soluble tripheno dioxazine compounds and their starting products containing sulfonyl groups, process for their preparation and use of these tripheno dioxazines as dyestuffs | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| WO-1993002711-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1993-02-18 | — | — | WO | disclosed |
| EP-0355492-B1 | REACTIVE DYES | BAYER AG (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-5138054-A | Colorfastness, photostability; red dye | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| US-5112970-A | Fiber reactive | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0258686-B1 | WATER SOLUBLE TRIPHENDIOXAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0212635-A1 | Water soluble triphenedioxazine compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4629788-A | COLORFASTNESS; BLUE COLOR; NATURAL AND SYNTHETIC FIBER | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-16 | — | — | US | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| US-4591643-A | Triphendioxazine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | disclosed |
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
| EP-0168751-A1 | Water soluble triphenedioxazine compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0158882-A2 | Triphenedioxazine dyes | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0148390-A2 | Basic triphendioxazine dyes, their manufacture and their use | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |
| EP-0144580-A2 | Triphendioxazine dyes | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |
| EP-0141996-A2 | Triphendioxazine reactive dyes | BAYER AG (DE) | 1985-05-22 | — | — | EP | disclosed |