Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720245 | 0.84 | TP53 (0.58) | MEN1KMT2AMAPTACHECYP1A2 | |
| SCHEMBL520733 | 0.83 | MEN1 (0.58) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL7911565 | 0.82 | MEN1 (0.64) | MEN1KMT2AHTTMAPTCYP1A2 | |
| SCHEMBL11670232 | 0.81 | TSHR (0.59) | MEN1KMT2AACHEALDH1A1THRA | |
| SCHEMBL31067505 | 0.80 | MAPT (0.67) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL4470153 | 0.80 | MAPT (0.67) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL4959727 | 0.80 | MAPT (0.55) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL521069 | 0.79 | MAPT (0.57) | MEN1KMT2AHTTMAPTCYP1A2 | |
| SCHEMBL27504159 | 0.79 | CYP4F2 (0.56) | KMT2AHTTMAPTL3MBTL1ACHE | |
| SCHEMBL3234327 | 0.79 | CES2 (0.68) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045298-A1 | ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |