Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | FGF1 | P05230 | 2/20 | 0.36 |
| ▸ | FGF2 | P09038 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 2/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705219 | 1.00 | CA1 (0.42) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL26879181 | 0.92 | CA1 (0.39) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL8720284 | 0.88 | CA1 (0.49) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL20147260 | 0.85 | FGF1 (0.40) | CA1CA2CA9BCHEACHE | |
| SCHEMBL16224526 | 0.84 | TUBB4A (0.38) | CA1CA2CA9BCHEACHE | |
| SCHEMBL29381346 | 0.81 | KCNA5 (0.47) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL14410760 | 0.80 | FGF1 (0.45) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL14410762 | 0.80 | FGF1 (0.45) | CA1CA2CA9TACR2NT5E | |
| SCHEMBL26879797 | 0.79 | — | — | |
| SCHEMBL28316892 | 0.79 | FGF1 (0.52) | CA1CA2CA9NT5EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |