Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54542 | 0.86 | ABL1 (0.52) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL8724561 | 0.82 | ADORA3 (0.38) | MAPTNPC1RAB9AENPP1ADORA3 | |
| SCHEMBL12843389 | 0.78 | SYK (0.53) | ABL1ABCB1BCRAPPALDH1A1 | |
| SCHEMBL8720361 | 0.78 | ABL1 (0.47) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL3794694 | 0.77 | NPC1 (0.51) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL14604251 | 0.77 | ABL1 (0.58) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL10304847 | 0.77 | ABL1 (0.53) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL321832 | 0.76 | ABL1 (0.62) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL13241127 | 0.75 | ABL1 (0.52) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL9679255 | 0.75 | SYK (0.48) | ABL1ABCB1BCRAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855390-A1 | A process for producing optically active pyrrolidine derivatives | Takasago International Corporation (JP) | 1998-07-29 | — | — | EP | disclosed |