Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CDK11B | P21127 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720486 | 0.86 | MAPT (0.46) | MEN1HTTKMT2AKDM4EMAPT | |
| SCHEMBL8720537 | 0.78 | CTSK (0.43) | KDM4EMAPTL3MBTL1LMNANPSR1 | |
| SCHEMBL8722832 | 0.77 | BRAF (0.45) | MEN1KMT2AKDM4EMAPTL3MBTL1 | |
| SCHEMBL8723515 | 0.77 | SLC6A2 (0.43) | KMT2AKDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL29608122 | 0.76 | KDM4E (0.50) | MEN1KMT2AKDM4EMAPTL3MBTL1 | |
| SCHEMBL8720669 | 0.73 | HTT (0.44) | MEN1HTTKMT2AKDM4EMAPT | |
| SCHEMBL23221440 | 0.69 | SLC6A2 (0.40) | MEN1KMT2AKDM4EMAPTL3MBTL1 | |
| SCHEMBL8667374 | 0.68 | MAPT (0.48) | MEN1HTTKMT2AKDM4EMAPT | |
| SCHEMBL8672947 | 0.68 | MAPT (0.50) | MEN1HTTKMT2AKDM4EMAPT | |
| SCHEMBL8666887 | 0.68 | MAPT (0.47) | MEN1HTTKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | disclosed |
| US-5759956-A | PYRAZINE CARBOXAMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0700391-A1 | HERBICIDAL COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027974-A1 | HERBICIDAL COMPOUNDS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-12-08 | — | — | WO | disclosed |