Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397986 | 0.83 | ABAT (0.74) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL11634169 | 0.77 | ALDH1A1 (0.66) | IDO1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5146332 | 0.77 | ALDH1A1 (0.60) | IDO1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7657194 | 0.76 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL8720521 | 0.76 | ALDH1A1 (0.57) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL7658700 | 0.76 | ALDH1A1 (0.67) | IDO1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10099725 | 0.75 | GAA (0.83) | IDO1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6096417 | 0.75 | GAA (0.62) | IDO1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5518500 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1GAACA1 | |
| SCHEMBL6816535 | 0.74 | MAPT (0.77) | MEN1KMT2APOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876354-A1 | 2-(SUBSTITUTED SULFANYL)-3,5-DIHYDRO-IMIDAZOL-4-ONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997019931-A1 | 2-(SUBSTITUTED SULFANYL)-3,5-DIHYDRO-IMIDAZOL-4-ONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | disclosed |
| US-5599829-A | FOR INCREASED HIGH DENSITY LIPOPROTEIN LEVELS IN BLOOD | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |