SCHEMBL6096417

SCHEMBL6096417

CCNC(=S)Nc1ccc(F)cc1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.62
ALDH1A1 P00352 3/20 0.62
MAPT P10636 2/20 0.62
HTT P42858 2/20 0.62
KDM4E B2RXH2 1/20 0.62
THRB P10828 1/20 0.62
MAPK1 P28482 1/20 0.62
LMNA P02545 2/20 0.61
KMT2A Q03164 4/20 0.59
IDO1 P14902 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MEN1 O00255 2/20 0.58
POLB P06746 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13761437 0.82 ALDH1A1 (0.65) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL5455321 0.82 SMN1; SMN2 (0.66) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL10099725 0.81 GAA (0.83) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL11072927 0.81 CYP1A2 (0.74) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL8611488 0.81 ALDH1A1 (0.81) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL14386215 0.81 SMN1; SMN2 (0.68) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL8979285 0.81 LMNA (0.70) GAAALDH1A1MAPTKDM4ELMNA
SCHEMBL14386106 0.80 LMNA (0.72) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL6068286 0.80 EPHX2 (0.58) GAAALDH1A1MAPTHTTKDM4E
SCHEMBL1275764 0.80 KMT2A (0.72) GAAALDH1A1MAPTHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263167-A1 METHOD OF PREPARING A BISMUTH SULFIDE PARTICLE CONTAINING ANTIBACTERIAL COMPOSITION IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-08-24 US disclosed
US-11700855-B2 Method for preventing or reducing growth of a microorganism on a surface IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-07-18 US disclosed
US-20210061670-A1 METHOD FOR PREVENTING OR REDUCING GROWTH OF A MICROORGANISM ON A SURFACE IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2021-03-04 US disclosed
US-10934176-B2 Methods of degrading organic pollutants and preventing or treating microbe using Bi2S3-CdS particles IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2021-03-02 US disclosed
US-20200102228-A1 METHODS OF DEGRADING ORGANIC POLLUTANTS AND PREVENTING OR TREATING MICROBE USING Bi2S3-CdS PARTICLES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2020-04-02 US disclosed
US-10105687-B1 Heterostructured Bi2S3—ZnS photocatalysts and methods thereof IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2018-10-23 US disclosed
US-7135492-B2 Increases the concentration of high density lipoprotein cholesterol in the blood; dyslipoproteinemia; angina pectoris, myocardial infarction, antiarrhythmia agents, heart failure, kidney failure stroke, peripheral arterial occulsion WYETH (US) 2006-11-14 US disclosed
US-20030119889-A1 1,3-Disubstituted-2- thioxo-imidazolidine-4,5-dione derivatives useful in the treatment of atherosclerosis WYETH 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030119889-A1 1,3-Disubstituted-2- thioxo-imidazolidine-4,5-dione derivatives useful in the treatment of atherosclerosis FFAR4, FFAR1, MSR1 GAA 4801/4885ALDH1A1 896/4885MAPT 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.