Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600740 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL26831413 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL8720509 | 0.81 | LMNA (0.51) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL20053799 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL12797606 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL19861782 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL21237806 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL19297200 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL19297194 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL22958087 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1LMNAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |