Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720539 | 0.86 | CACNA1I (0.40) | KMT2ASCN9AALDH1A1 | |
| SCHEMBL7963938 | 0.85 | ALDH1A1 (0.42) | KMT2ASCN9ASCN10AALDH1A1CYP3A4 | |
| SCHEMBL8720597 | 0.83 | KMT2A (0.39) | KMT2ASCN9AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8721664 | 0.83 | KCNT1 (0.40) | KMT2AALDH1A1CYP3A4HSD17B10KCNT1 | |
| SCHEMBL8720745 | 0.82 | CHRNB2 (0.40) | KMT2ASCN9AALDH1A1KCNT1ADORA2A | |
| SCHEMBL8725888 | 0.82 | CBLB (0.45) | KMT2ASCN10AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8725981 | 0.82 | XPO1 (0.40) | KMT2ASCN10AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8725971 | 0.81 | SCN9A (0.41) | KMT2ASCN9AALDH1A1 | |
| SCHEMBL8721842 | 0.81 | ALDH1A1 (0.41) | KMT2ASCN9AALDH1A1 | |
| SCHEMBL8721044 | 0.81 | ALDH1A1 (0.46) | KMT2AALDH1A1CYP3A4HSD17B10STIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | claimed |