Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723510 | 0.90 | MAPT (0.52) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8721730 | 0.81 | KDR (0.52) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL4765801 | 0.80 | MAPT (0.45) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8721892 | 0.80 | KDR (0.49) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8721890 | 0.79 | NPSR1 (0.57) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8721009 | 0.79 | MAPT (0.55) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8720496 | 0.78 | ALDH1A1 (0.50) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8720486 | 0.78 | MAPT (0.46) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8720532 | 0.77 | POLB (0.46) | MAPTBRAFKDRMAPK14TNNI3K | |
| SCHEMBL8722832 | 0.76 | BRAF (0.45) | MAPTBRAFKDRMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | claimed |