Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21246763 | 0.81 | DPP7 (0.33) | SCN4A | |
| SCHEMBL15024073 | 0.79 | NOS2 (0.33) | SCN4A | |
| SCHEMBL2183860 | 0.79 | REN (0.33) | SCN4A | |
| SCHEMBL28539257 | 0.79 | SCN4A (0.33) | SCN4A | |
| SCHEMBL1369574 | 0.77 | SLC7A5 (0.35) | SLC7A5SCN4ASLC1A3SLC1A2 | |
| D-Glutamate SCHEMBL22833968 | 0.77 | SLC1A3 (0.45) | SLC7A5GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15663464 | 0.76 | SCN4A (0.40) | SCN4ACYP1A2 | |
| SCHEMBL2083660 | 0.76 | — | — | |
| SCHEMBL28542946 | 0.76 | DPP4 (0.32) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL2181473 | 0.75 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570244-B1 | Process for preparing peptides having a C-terminal proline amide | SANKYO CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0570244-A1 | Process for preparing peptides having a c-terminal proline amide | SANKYO COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |