Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 16/20 | 0.43 |
| ▸ | HTR1B | P28222 | 14/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381711 | 0.94 | SLC6A4 (0.45) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8722085 | 0.91 | HTR1A (0.51) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL7481219 | 0.85 | HTR1D (0.46) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL8383598 | 0.85 | SLC6A4 (0.47) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL7489507 | 0.85 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL8387183 | 0.84 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8724293 | 0.83 | HTR6 (0.49) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| Fumaric Acid SCHEMBL8382079 | 0.82 | HTR1D (0.41) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8722115 | 0.80 | SLC6A4 (0.50) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL8725963 | 0.80 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR1FSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |