Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717928 | 0.86 | TACR1 (0.40) | TACR1 | |
| SCHEMBL8720600 | 0.76 | TACR1 (0.37) | TACR1 | |
| SCHEMBL8912656 | 0.66 | TACR1 (0.46) | TACR1 | |
| SCHEMBL8717852 | 0.66 | TACR1 (0.46) | TACR1 | |
| SCHEMBL8201272 | 0.66 | TACR1 (0.36) | TACR1 | |
| SCHEMBL8201944 | 0.66 | TACR1 (0.38) | TACR1 | |
| SCHEMBL8201255 | 0.64 | TACR1 (0.32) | TACR1 | |
| SCHEMBL13059859 | 0.63 | LIG1 (0.38) | TACR1 | |
| SCHEMBL8201401 | 0.63 | GRIN2D (0.35) | TACR1 | |
| SCHEMBL8201999 | 0.63 | GRIN2D (0.36) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880529-A1 | SPIRO-KETAL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 1998-12-02 | — | — | EP | claimed |
| WO-1997030056-A1 | SPIRO-KETAL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-08-21 | — | — | WO | claimed |