Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716156 | 0.67 | — | — | |
| SCHEMBL8716221 | 0.67 | — | — | |
| SCHEMBL8259600 | 0.64 | GABRA1 (0.52) | GABRA1GABRB2SRD5A1ESR1ESR2 | |
| SCHEMBL23685407 | 0.63 | GABRA1 (0.46) | GABRA1GABRB2L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL5450147 | 0.62 | GABRA1 (0.53) | GABRA1GABRB2L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL69697 | 0.62 | TYR (0.58) | GABRA1GABRB2MEN1ALDH1A1KMT2A | |
| SCHEMBL1230588 | 0.62 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL17472450 | 0.62 | GABRA1 (0.36) | GABRA1GABRB2SRD5A1 | |
| SCHEMBL15676646 | 0.61 | GABRA1 (0.64) | GABRA1GABRB2L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL1006107 | 0.61 | XDH (0.70) | GABRA1GABRB2SRD5A1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847149-A | Thiadiazole derivatives, process for their preparation, and their use as precursors for the production of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |