Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24236653 | 0.74 | — | — | |
| SCHEMBL7684177 | 0.71 | HTT (0.46) | HTT | |
| SCHEMBL19783978 | 0.69 | METAP2 (0.39) | METAP2 | |
| SCHEMBL13918274 | 0.68 | SMN1; SMN2 (0.36) | ADORA2AADORA2B | |
| SCHEMBL23564729 | 0.68 | HTT (0.46) | HTT | |
| SCHEMBL21747697 | 0.65 | PDE4B (0.36) | — | |
| SCHEMBL22206420 | 0.63 | PKM (0.44) | HTT | |
| SCHEMBL21803323 | 0.63 | PKM (0.47) | — | |
| SCHEMBL9232299 | 0.62 | HTT (0.54) | HTT | |
| SCHEMBL21493503 | 0.61 | KDM4E (0.44) | HTTADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567982-B1 | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5466820-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0567982-A1 | Azole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |