Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCN1 | O60741 | 3/20 | 0.38 |
| ▸ | HCN4 | Q9Y3Q4 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909087 | 1.00 | HCRTR1 (0.39) | HCRTR1KMT2AHCN1HCN4CNR1 | |
| SCHEMBL8720655 | 0.95 | PNLIP (0.41) | HCRTR1HCN1HCN4DRD2SLC6A4 | |
| SCHEMBL30909140 | 0.95 | PNLIP (0.41) | HCRTR1HCN1HCN4DRD2SLC6A4 | |
| SCHEMBL8722156 | 0.86 | DRD2 (0.38) | DRD2SLC6A4OPRK1HRH3 | |
| SCHEMBL30909070 | 0.85 | TDP1 (0.38) | KMT2AHTR1AOPRK1HRH3 | |
| SCHEMBL8721187 | 0.85 | TDP1 (0.38) | KMT2AHTR1AOPRK1HRH3 | |
| SCHEMBL30908934 | 0.83 | ALDH1A1 (0.44) | HCRTR1KMT2AAVPR1A | |
| SCHEMBL8723596 | 0.83 | ALDH1A1 (0.44) | HCRTR1KMT2AAVPR1A | |
| SCHEMBL30909135 | 0.81 | HCRTR1 (0.39) | HCRTR1KMT2AHCN1HCN4CNR1 | |
| SCHEMBL8721780 | 0.81 | HCRTR1 (0.39) | HCRTR1KMT2AHCN1HCN4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |