Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MYOC | Q99972 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233933 | 0.84 | RAF1 (0.49) | MEN1KMT2ALMNAPOLBRAF1 | |
| SCHEMBL10817393 | 0.83 | ALDH1A1 (0.56) | MEN1KMT2ALMNAALDH1A1CYP3A4 | |
| SCHEMBL8728027 | 0.83 | SRD5A2 (0.54) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL16792372 | 0.82 | ALDH1A1 (0.57) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL4788024 | 0.82 | PKM (0.59) | MEN1KMT2ALMNAPOLBRAF1 | |
| SCHEMBL4788031 | 0.80 | KDR (0.52) | MEN1KMT2ARAF1ALDH1A1MAPT | |
| SCHEMBL4688156 | 0.79 | BRAF (0.51) | MEN1KMT2ALMNARAF1ALDH1A1 | |
| SCHEMBL4687895 | 0.79 | MEN1 (0.60) | MEN1KMT2ALMNAPOLBRAF1 | |
| SCHEMBL1028021 | 0.79 | MEN1 (0.47) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL7937740 | 0.78 | TDP1 (0.50) | MEN1KMT2ALMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |