Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7654459 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL6452586 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL8722324 | 0.65 | MEN1 (0.37) | MAPTCYP3A4SMN1; SMN2KDM4EHTT | |
| SCHEMBL6438664 | 0.64 | MEN1 (0.39) | MAPTCYP3A4SMN1; SMN2KDM4EHTT | |
| Hydrochloric Acid SCHEMBL5178267 | 0.63 | SMN1; SMN2 (0.32) | MAPTCYP3A4SMN1; SMN2KDM4EHTT | |
| Hydrochloric Acid SCHEMBL8722331 | 0.62 | MEN1 (0.37) | MAPTCYP3A4SMN1; SMN2KDM4EHTT | |
| SCHEMBL3690826 | 0.62 | CALM1 (0.42) | MAPTCYP3A4KDM4EPOLB | |
| SCHEMBL9244022 | 0.62 | CALM1 (0.42) | MAPTCYP3A4KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL1070852 | 0.61 | MAPT (0.36) | MAPTCYP3A4SMN1; SMN2KDM4EHTT | |
| SCHEMBL9064080 | 0.59 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874006-A1 | Polymerisation of olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-10-28 | — | — | EP | disclosed |