SCHEMBL872238

SCHEMBL872238

Cc1ccc(-c2cnc[nH]2)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.64
ASIC3 Q9UHC3 2/20 0.64
POLB P06746 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
CYP3A4 P08684 3/20 0.63
MAPT P10636 1/20 0.55
LTA4H P09960 1/20 0.55
CYP2D6 P10635 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2E1 P05181 1/20 0.52
CYP2A6 P11509 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2B6 P20813 1/20 0.52
CYP2C19 P33261 1/20 0.52
CYP11B1 P15538 1/20 0.52
CYP11B2 P19099 1/20 0.52
HPGDS O60760 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17800997 0.86 IDO1 (0.75) IDO1ASIC3POLBSMN1; SMN2CYP3A4
Ethoxycarbonyl Group SCHEMBL29213504 0.81 CYP3A4 (0.50) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL27880327 0.80 IDO1 (0.67) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL30859371 0.79 IDO1 (0.41) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL14318037 0.79 IDO1 (0.55) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL14705340 0.78 IDO1 (0.64) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL496675 0.78 IDO1 (0.64) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL482297 0.78 IDO1 (0.64) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL17782163 0.78 ASIC3 (1.00) IDO1ASIC3POLBSMN1; SMN2CYP3A4
SCHEMBL205481 0.78 IDO1 (0.64) IDO1ASIC3POLBSMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528801-B2 Substituted azacyles as TRPM8 modulators GIVAUDAN SA (CH) 2026-01-20 US claimed
EP-4525821-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT Firmenich Incorporated (US) 2025-03-26 EP claimed
WO-2024011086-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-01-11 WO claimed
CN-116425681-A Green synthesis method of cyazofamid 青岛农业大学 2023-07-14 CN claimed
EP-4045491-A1 SUBSTITUTED AZACYLES AS TRMP8 MODULATORS Givaudan SA (CH) 2022-08-24 EP claimed
CN-108912052-B Preparation method of cyazofamid 江苏扬农化工集团有限公司 2020-08-14 CN claimed
CN-110359295-A A kind of preparation method of multi-functional long wavelength's long-life phosphors cotton fabric based on Cd-MOF 东华大学 2019-10-22 CN claimed
CN-110003483-A The preparation method of zeolite imidazole frame structure material 中国科学院宁波材料技术与工程研究所 2019-07-12 CN claimed
CN-108951158-A A kind of nano-composite fiber film and preparation method thereof 厦门理工学院 2018-12-07 CN claimed
CN-108912052-A A kind of preparation method of cyazofamid 江苏扬农化工集团有限公司 2018-11-30 CN claimed
CN-103446893-B Method for preparing metal organic framework membrane on inner wall of tubular ceramic support NANJING TECH UNIVERSITY (CN) 2015-09-02 CN claimed
CN-103464107-B Preparation method of ZIFs/LDHs composite material UNIV TAIYUAN TECHNOLOGY 2015-05-06 CN claimed
CN-103464107-A Preparation method of ZIFs/LDHs composite material UNIV TAIYUAN TECHNOLOGY 2013-12-25 CN claimed
CN-103446893-A Method for preparing metal organic framework membrane on inner wall of tubular ceramic support NANJING UNIVERSITY OF TECHNOLOGY 2013-12-18 CN claimed
CN-103224535-A Metal or ligand replacement method for construction of mixed metal or mixed ligand zeolitic imidazolate frameworks (ZIFs) DALIAN CHEMICAL PHYSICS INST 2013-07-31 CN claimed
CN-101311215-B Organic protective film composition DONGJIN SEMICHEM CO LTD 2013-02-06 CN claimed
CN-101912737-B Method for preparing metal organic framework supported film NANJING UNIVERSITY OF TECHNOLOGY 2012-12-19 CN claimed
CN-102351800-A Method for preparing 5-methylbenzimidazole-2-methyl carbamate UNIV NANJING FORESTRY 2012-02-15 CN claimed
CN-101912737-A Method for preparing metal organic framework supported film NANJING UNIVERSITY OF TECHNOLOGY 2010-12-15 CN claimed
CN-101311215-A Organic protective film composition DONGJIN SEMICHEM CO LTD (KR) 2008-11-26 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528801-B2 Substituted azacyles as TRPM8 modulators TRPM8, TRPM7, TRPM4 IDO1 1885/4885ASIC3 93/4885POLB 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.