Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418064 | 0.79 | HPGD (0.54) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL8727089 | 0.79 | MEN1 (0.38) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL8725280 | 0.79 | CYP2D6 (0.44) | ALDH1A1L3MBTL1ALOX12TDP1LMNA | |
| SCHEMBL72023 | 0.78 | HSD17B10 (0.50) | ALDH1A1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL8721609 | 0.78 | KMT2A (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL8718097 | 0.76 | GAA (0.44) | ALDH1A1RAB9ANPC1HPGDPOLB | |
| SCHEMBL3932390 | 0.76 | NPC1 (0.41) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL8938873 | 0.76 | MEN1 (0.39) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL6440705 | 0.75 | RAB9A (0.55) | NFKB1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2749867 | 0.74 | ALDH1A1 (0.62) | NFKB1ALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |